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Another study in The New England Journal of Medicine suggests a correlation between oral sex and throat cancer.It is believed that this is due to the transmission of HPV, a virus that has been implicated in the majority of cervical cancers and which has been detected in throat cancer tissue in numerous studies.Oral sex may be practiced by people of any sexual orientation.

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The study concludes that people who had one to five oral sex partners in their lifetime had approximately a doubled risk of throat cancer compared with those who never engaged in this activity and those with more than five oral sex partners had a 250 percent increased risk.

Fellatio may reduce the risk of miscarriages by inducing immunological tolerance in the woman by exposure to the proteins in her partner's semen, a process known as paternal tolerance.

In humans, there is no connection between the gastrointestinal system and the reproductive system, and sperm ingested by the woman would be killed and broken down by acids in her stomach and proteins in the small intestine.

The breakdown products are then absorbed as a negligible quantity of nutrients.

Because of the aforementioned factors, medical sources advise the use of condoms or other effective barrier methods when performing or receiving oral sex with a partner whose STI status is unknown.

Links have been reported between oral sex and oral cancer with human papillomavirus (HPV)-infected people.

Certain kinds of plastic wrap are manufactured to be microwaveable and are designed to have pores that open when heated, but there also exists no scientific research on what effect, if any, this has on disease transmission when used during oral sex.

Some people complain that the thickness of the plastic dulls sensation.

but using a real dental dam is seen as preferable; this is because real dental dams cover a larger area, avoid accidents caused by "slipping" outside the covered area, and avoid the risk that makeshift versions may be accidentally damaged or poked with the scissors during the cutting procedure.

Plastic wrap may also be used as a barrier during oral sex, but there exists no conclusive scientific research regarding how effective it may or may not be at preventing disease transmission.

A report issued in September 2005 by the National Center for Health Statistics was the basis of an article in the September 26, 2005 issue of Time magazine.